430 Results for "

Calystegia sepium (Linn.) R. Br.

" in MedChemExpress (MCE) Product Catalog:
Products (430)

430 Results for "Calystegia sepium (Linn.) R. Br." in MCE Product Catalog:

53
53 Publications Verification
Cat. No.: HY-13251
CAS No.: 697235-38-4
Purity:  99.96%
Synonyms: (-)-Silvestrol
Silvestrol is a eukaryotic translation initiation factor 4A (eIF4A) inhibitor isolated from Agave americana Linn.. Silvestrol induces autophagy and caspase-mediated apoptosis .
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39
39 Cited Publications
Cat. No.: HY-12306
CAS No.: 76939-46-3
Purity:  99.91%
Synonyms: 8-Br-Camp sodium salt
Target:  

PKA Apoptosis

Research Areas:  

Cancer

8-Bromo-cAMP sodium (8-Br-Camp) sodium salt, a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA). 8-Bromo-cAMP sodium salt has anti-proliferative and apoptotic effects against cancer cells .
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39
39 Cited Publications
Cat. No.: HY-12306A
CAS No.: 23583-48-4
Purity:  99.48%
Synonyms: 8-Br-Camp
Target:  

PKA Apoptosis

Research Areas:  

Cancer

8-Bromo-cAMP (8-Br-Camp), a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA). 8-Bromo-cAMP has anti-proliferative and apoptotic effects against cancer cells .
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14
14 Cited Publications
Cat. No.: HY-N0622
CAS No.: 62596-29-6
Synonyms: Mulberrochromene
Morusin is a prenylated flavonoid isolated from Morus alba Linn. with various biological activities, such as antitumor, antioxidant, and anti-bacteria property. Morusin could inhibit NF-κB and STAT3 activity.
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14
14 Cited Publications
Cat. No.: HY-N0013
CAS No.: 3681-93-4
Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects .
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11
11 Cited Publications
Cat. No.: HY-N0116
CAS No.: 517-28-2
Synonyms: Natural Black 1; Haematoxylin
Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
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10
10 Cited Publications
Cat. No.: HY-13065
CAS No.: 20784-50-3
Purity:  99.01%
Synonyms: Corylifolinin; Isobacachalcone
Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity .
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9
9 Cited Publications
Cat. No.: HY-129393
CAS No.: 2239273-34-6
Purity:  99.67%
Synonyms: AB928
Target:  

Adenosine Receptor

Research Areas:  

Inflammation/Immunology Cancer

Etrumadenant (AB928) is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist. Etrumadenant relieves adenosine-mediated immune suppression. Etrumadenant has immunomodulatory and antitumor activities .
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6
6 Cited Publications
Cat. No.: HY-N1381
CAS No.: 13137-64-9
Periplocin is a cardiotonic steroid isolated from root-bark Periploca sepium Bunge. Periplocin promotes tumor cell apoptosis and inhibits tumor growth. Periplocin has the potential to facilitate wound healing through the activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase .
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4
4 Cited Publications
Cat. No.: HY-B0566
CAS No.: 23256-50-0
Synonyms: BR-750; Wy8678 acetate
Guanabenz (Acetate) (BR-750) is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.
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4
4 Cited Publications
Cat. No.: HY-50730
CAS No.: 2224-02-4
Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor .
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4
4 Cited Publications
Cat. No.: HY-B0780
CAS No.: 247257-48-3
Synonyms: BR-A-657
Fimasartan (BRA-657) is an orally effective angiotensin receptor AT1 non-peptide antagonist. Fimasartan has antihypertensive effects. Fimasartan improves neuroinflammation and brain injury mediated by NLRP3 inflammatome after intracerebral hemorrhage, and has neuroprotective effect. Fimasartan inhibits the expression of inducible nitric oxide synthase through the inactivation of NF-κB and activator protein-1 .
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3
3 Cited Publications
Cat. No.: HY-D1396
CAS No.: 2387906-44-5
Research Areas:  

Others

Br-DAPI is a marker dye in DAPI series. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. DAPI cannot penetrate intact cell membranes and is commonly used for staining damaged and fixed cells . Storage: Keep away from light.
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3
3 Cited Publications
Cat. No.: HY-103169
CAS No.: 316173-57-6
Purity:  99.94%
Target:  

Adenosine Receptor

Research Areas:  

Neurological Disease

SCH442416 is a potent, selective and brain-penetrant antagonist of adenosine A2A receptor (A2AR), with Kis of 0.048 and 0.5 nM for human and rat A2AR respectively. SCH442416 displays more than 23000-fold selectivity over A1R, A2BR, and A3R (Ki=1111, 10000, and 10000 nM, respectively). SCH442416 can be used for imaging of adenosine A2A receptors in rat and primate brain .
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2
2 Cited Publications
Cat. No.: HY-B0460
CAS No.: 411207-31-3
Synonyms: BA-679 BR monohydrate
Target:  

mAChR

Research Areas:  

Inflammation/Immunology

Tiotropium bromide monohydrate (BA-679 BR monohydrate) is a long-acting anticholinergic bronchodilator. Tiotropium bromide monohydrate blocks the action of acetylcholine at muscarinic M1, M2, and M3 receptors, prevents bronchoconstriction, and dilates bronchial airways. Tiotropium bromide monohydrate is applicable to research related to chronic obstructive pulmonary disease and asthma .
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2
2 Cited Publications
Cat. No.: HY-17360
CAS No.: 136310-93-5
Synonyms: BA679 BR
Target:  

mAChR

Research Areas:  

Inflammation/Immunology

Tiotropium bromide (BA-679 BR) is a long-acting anticholinergic bronchodilator. Tiotropium bromide blocks the action of acetylcholine at muscarinic M1, M2, and M3 receptors, prevents bronchoconstriction, and dilates bronchial airways. Tiotropium bromide is applicable to research related to chronic obstructive pulmonary disease and asthma .
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2
2 Cited Publications
Cat. No.: HY-75342
CAS No.: 3943-74-6
Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator . A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.
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2
2 Cited Publications
Cat. No.: HY-121161A
CAS No.: 280129-83-1
Purity:  99.71%
Target:  

Cytochrome P450

Research Areas:  

Others

Brassinazole is a selective triazole-type brassinosteroid (BR) biosynthesis inhibitor. Brassinazole is used for regulating plant growth and development .
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2
2 Cited Publications
Cat. No.: HY-12524
CAS No.: 188011-69-0
Purity:  99.96%
Synonyms: Abrasin
Target:  

GSK-3

Research Areas:  

Others

Bikinin is a non-steroidal, ATP-competitive inhibitor of plant GSK-3/Shaggy-like kinases and activates BR (brassinosteroids) signaling.
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2
2 Cited Publications
Cat. No.: HY-N0013R
CAS No.: 3681-93-4
Vitexin (Standard) is the analytical standard of Vitexin. This product is intended for research and analytical applications. Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects .
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